How Interferon-Gamma ELISA Kits Advance Cytokine Research in Autoimmune Diseases
Interferon‑gamma (IFN‑γ) is a type of protein known as a cytokine that plays a vital role in the body’s immune system. It belongs to the type II interferon family and is distinct from type I interferons (like IFN-α and IFN-β).
It is mainly produced by immune cells, such as:
T helper 1 (Th1) cells
Cytotoxic T cells (CD8⁺)
Natural Killer (NK) cells
NKT cells
Its primary functions are:
To activate macrophages to kill intracellular pathogens, such as viruses and bacteria.
To boost antigen presentation by increasing MHC class I and II molecule expression.
To direct immune responses toward Th1-type immunity, which is more inflammatory and cell-mediated.
To inhibit Th2 responses, which are associated with allergies and humoral immunity.
To regulate inflammati...